Conference: 5th International Conference on Quality and Evidence Based in Prophetic Medicine
Keywords: Polycystic ovaries syndrome; Hijama; Wet cupping.
Objective: To assess the effectiveness of cupping therapy on the endocrine and metabolic indicators opatients with polycystic ovarian syndrome. The primary outcome measured was the effect on thereproductive hormonal profile and metabolites before and after Hijama. The secondary outcome measured was pregnancy rates after Hijama. Prophetic medicine recommended Al-Hijama and considered it as the best remedy.
Methods: Research Design. This study was a pilot clinical study.
Setting: The study was conducted at Prophetic Medicine Research Clinic, King Abdulaziz University, Jeddah, Saudi Arabia at the period between January 2013 to December 2016.
Sample: Forty-one women (38 married (25 from them have infertility) and 3 unmarried). All patients signed consent. They followed one year before cupping therapy and stopped medical treatment three months before it, they received cupping therapy for three consecutive months. Inclusion criteria: women aged from 25-45 years old diagnosed polycystic ovarian syndrome. We excluded other causes of hyperandrogenisis, syndromes of severe insulin resistance, Late onset non-classic 21 hydroxylase deficiency, ovarian androgen-secreting tumors, use of anabolic or androgenic drugs, Cushing’s syndrome, hypothalamic and pituitary disorders causing amenorrhea, premature ovarian failure, we assessed in all patient before and after cupping therapy the following thyroid stimulating hormone, luteinizing hormone, testosterone, follicle-stimulating hormone, prolactin, estradiol, progesterone, fasting blood glucose, total cholesterol, triglycerides, high-density lipoprotein and C-reactive protein.
Tools: a) Structured interview questionnaire. (b) Polycystic ovarian syndrome questionnaire. (c) Venous blood was collected from all patients and routine blood biochemical, hormonal and metabolic factors assessment were performed before wet cupping and then three months after cupping in second day of menstrual cycle. (d) Wet cupping was performed on the study subjects for three consecutive months in the second day of menstrual cycle. We made data entry to SPSS statistical software version 20, 0.
Results: According to the results at baseline in all study group, there were higher levels than normal of thyroid stimulating hormone, luteinizing hormone, estradiol and C-reactive protein by (9.76%), (56.10%), (90.24%), and (68.29%), respectively. In all patients, there were higher level than normal of prolactin, testosterone, and triglycerides, but there was lower level than normal of progesterone in all patients. We found lower level than normal of follicle-stimulating hormone in (19.51%), FBS in (82.93%) and high-density lipoprotein in (39. 02%). We found normal level of total cholesterol in all patients, also we found the obesity in (2.44%).
After cupping therapy six patients get pregnancy 6/25 (24%), the prolactin hormone was reduced significantly (p<0.05) and high-density lipoprotein was increased significantly (p<0.05), there was significant difference between before Hijama and after Hijama according to luteinizing hormone / Follicle-stimulating hormone ratio (p<0.05).
Conclusion: From the whole previous points, we conclude that wet cupping was an adequate and safe technique, might be associated with improvement of symptoms of polycystic ovarian syndrome.